PhD Student - Position

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PhD student position (Doktorand) available from July 1st 2024 at the Hearing Research Centre of the University of Tübingen

The position is embedded in the Graduate Training Center “cGMP: from Bench to Bedside” (Graduiertenkolleg GRK 2381) of the Deutsche Forschungsgemeinschaft (DFG). The doctoral position is supervised by Prof. Marlies Knipper and Prof. Lukas Rüttiger in the Section Molecular Physiology of Hearing at the Hearing Research Centre of the University ENT-clinic (HNO) and the Centre for Neurosensory Systems (ZfN).


The research project studies the role of the cellular signalling molecule cGMP in an interdisciplinary team. cGMP is a “second messenger” for metabolism, development and growth, but also for protection and regeneration of sensory systems.


The PhD candidate will study interactions of the stress pathways and cGMP signaling with central auditory processing and autism spectrum disorders. Age- and noise-induced hearing loss will be considered.
The following questions will be addressed:


• Analyze the expression of molecular components of the cGMP signaling cascade (NO-GC/GC-A) during the development of hearing function and test pharmacological manipulation.
• Analyze how neuronal ion channels that are controlled by cGMP (BK channels) are involved in autism spectrum disorder.
• Analyze the influence of stress hormone receptors (MR/GR) on the cGMP signaling cascade (genetic deletion of MR/GR receptors in a mouse model).
• Analyze memory function in a model for impaired cGMP signaling including long-term potentiation, neuro-vascular coupling and functional gain after GC-A deletion.


The doctoral program is accompanied by a curricular program including general lectures and courses in neuroscience with a focus on neuro-sensory systems. The program expressly supports and recommends an international internship at our collaborative partner at the Tufts University in Boston, MA, USA (Prof. Michele Jacob), who is co-advisor of the doctoral thesis.


The position requires a MSc or a Diploma in Natural Science. The successful candidate bears a curiosity in neurosciences and is particularly interested in how sensory information is processed in the brain. The candidate will contribute significantly in designing, conducting and analyzing experiments.
The doctoral thesis will be supervised in a multi-disciplinary team. Molecular and histochemical techniques are established. In vivo testing for the hearing of laboratory animals require knowledge on neuronal information processing and sensory physiology. A Felasa B Course or equivalent as well as computer and mathematical skills are advantageous.


Please send curriculum vitae and references preferably by email to:
Wibke.singer@uni-tuebingen.de
voice: 07071-2988243

PhD Position: Preclinical Development of Individualized Antisense Oligonucleotides (ASOs) for Rare Neurological Diseases at the Hertie Institut for Clinical Brain Research

Find informations to the PhD position here:

https://www.hih-tuebingen.de/fileadmin/web/img/content/Karriere/Ausschreibungen/20231010_HIH_Stellenausschreibung_PhD.pdf

 

 

PhD position in Human Vision and Psychophysics (m/f/d)

The Department of Sensory and Sensorimotor Systems (PI Prof. Li Zhaoping) at the Max Planck Institute for Biological Cybernetics and at the University of Tübingen is currently looking for highly skilled and motivated individuals to work on projects aimed towards understanding visual attentional and perceptual processes using fMRI/MRI, TMS and/or EEG methodologies. The framework and motivation of the projects can be found at
https://www.lizhaoping.org/zhaoping/AGZL_HumanVisual.html.
The projects can involve one or more of the following tasks, for example, visual search tasks, stereo vision tasks, visual illusions. Research methods can involve one or more of the following, for example, fMRI/MRI technology, eye tracking, TMS and/or EEG methodologies, and computational modelling and other related methods as necessary. The explicit project and research methodology can be discussed in a case by case basis during the application process.
Responsibilities:
•    Conduct and participate in research projects such as lab and equipment set up, data collection, data analysis, writing reports and papers, and presenting at scientific conferences.
•    Participate in routine laboratory operations, such as planning and preparations for experiments, lab maintenance and lab procedures.
•    Participate in teaching assistance duties for university courses in our field.
Requirements:
•    Master’s degree in neuroscience, psychology, computer science, physics or a related natural science or engineering field.
•    Programming skills in MATLAB or Python or a similar language is required.
•    Skills in techniques of human visual psychophysics, experimental data taking, data analysis is highly desirable.
•    Skilled in report writing, previous peer reviewed publication is highly desirable.
•    Familiarity with hardware and techniques in one of the following techniques: eye tracking, fMRI/MRI, EEG, TMS, tDCS/tACS, and other related techniques such as in carrying out fMRI experiments is a plus.
•    Strong command of English; knowledge of German is a plus.           
Who we are:
We use a multidisciplinary approach to investigate sensory and sensory-motor transforms in the brain (www.lizhaoping.org). Our approaches consist of both theoretical and experimental techniques including human psychophysics, fMRI imaging, EEG, electrophysiology and computational modelling. One part of our group is located in the University, in the Centre for Integrative Neurosciences (CIN), and the other part is in the Max Planck Institute for Biological Cybernetics as the Department for Sensory and Sensorimotor Systems. You will have the opportunity to learn skills from other members of the group and benefit from multidisciplinary interactions, including with our collaborators locally and internationally. The PhD contract (TVöD-Bund E13, 65%) duration is for 3 years. We seek to raise the number of women in research and teaching and therefore urge qualified women to apply. Disabled persons will be preferred in case of equal qualification.
Your application:
The position is available immediately and will be open until filled. We look forward to receiving your application that includes (1) a cover letter,  including a statement on roughly when you would like to start this position, (2) a motivation statement, (3) a CV, (4) names and contact details of three people for references,  (5) transcripts from your past and current education listing the courses taken and their grades, (6) if you have them, please also include copies of your degree certificates, (7) if you have them, include a pdf file of your best publication(s), or other documents and information that you think could strengthen your application. Please use a single pdf file for these documents and send it to jobs.li@tuebingen.mpg.de, where also informal inquiries can be addressed. Please note that applications without complete information in (1)-(5) will not be considered, unless the cover letter includes an explanation and/or information about when the needed materials will be supplied.
For further opportunities in our group, please visit https://www.lizhaoping.org/jobs.html

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Postdoc - Positions

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Postdoctoral position in Human Vision and Psychophysics (m/f/d)

The Department of Sensory and Sensorimotor Systems (PI Prof. Li Zhaoping) at the Max Planck Institute for Biological Cybernetics and at the University of Tübingen is currently looking for highly skilled and motivated individuals to work on projects aimed towards understanding visual attentional and perceptual processes. The framework and motivation of the projects can be found at: https://www.lizhaoping.org/zhaoping/AGZL_HumanVisual.html.
The projects can involve one or more of the following tasks, for example, visual search tasks, stereo vision tasks, visual illusions. Research methods can involve one or more of the following, for example, fMRI/MRI technology, eye tracking, TMS and/or EEG methodologies, and computational modelling and other related methods as necessary. The explicit project and research methodology can be discussed in a case by case basis during the application process. The postdoc will be working closely with the principal investigator and other members of Zhaoping's team when needed.

Responsibilities:
•    Conduct and participate in research projects such as lab and equipment set up, data collection, data analysis, writing reports and papers, and presenting at scientific conferences.
•    Participate in routine laboratory operations, such as planning and preparations for experiments, lab maintenance and lab procedures.
•    Coordinate with the PI and other team members for strategies and project planning.
•    Coordinate with the PI and other team members for project planning, and in supervision of student projects or teaching assistance for university courses in our field.

Requirements:

•    Ph.D. in neuroscience, psychology, computer science, physics or a related natural science or engineering field.
•    Publications in peer-reviewed journals.
•    Highly skilled in techniques of human visual psychophysics such as eye tracking, MATLAB programming for experiments, experimental data taking, data analysis, and paper writing.
•    Experience in project management is highly desired.
•    Strong command of English; knowledge of German is a plus.

Who we are:
We use a multidisciplinary approach to investigate sensory and sensorimotor transforms in the brain (www.lizhaoping.org). Our approaches consist of both theoretical and experimental techniques including human psychophysics, fMRI imaging, EEG/ERP, and computational modelling. One part of our group is located in the University, in the Centre for Integrative Neurosciences (CIN), and the other part is in the Max Planck Institute (MPI) for Biological Cybernetics as the Department for Sensory and Sensorimotor Systems. You will have the opportunity to learn other skills in our multidisciplinary group and benefit from interactions with our colleagues in the university, at MPI, as well as internationally. This job opening is for the CIN or the MPI working group. The position (salary level TVöD-Bund E13, 100%) is for a duration of two years. Extension or a permanent contract after two years is possible depending on situations. We seek to raise the number of women in research and teaching and therefore urge qualified women to apply. Disabled persons will be preferred in case of equal qualification.

Your application:
The position is available immediately and will be open until filled. We look forward to receiving your application that includes (1) a cover letter, including a statement on roughly when you would like to start this position, (2) a motivation statement, (3) a CV, (4) names and contact details of three people for references, (5) if you have them, transcripts from your past and current education listing the courses taken and their grades, (6) if you have them, please also include copies of your degree certificates, (7) you may include a pdf file of your best publication(s), or other documents and information that you think could strengthen your application. Please use a single pdf file for these documents and send it to jobs.li@tuebingen.mpg.de, where also informal inquiries can be addressed. Please note that applications without complete information in (1)-(4) will not be considered, unless the cover letter includes an explanation and/or information about when the needed materials will be supplied.

For further opportunities in our group, please visit https://www.lizhaoping.org/jobs.html