TNC Virtual Neurocolloquium - Danielle S. Bassett

Danielle S. Bassett presents her work in the TNC’s virtual Neurocolloquium on June 10th, at 17:00.

Speaker: Danielle S. Bassett
Complex Systems Lab at University of Pennsylvania & Santa Fe Institute

Title: “Advances in Computational Psychiatry: Understanding (cognitive) control as a network process”

Host: Roxana Zeraati (GTC & MPI for Biological Cybernetics)

The human brain is a complex organ characterized by heterogeneous patterns of interconnections. Non-invasive imaging techniques now allow for these patterns to be carefully and comprehensively mapped in individual humans, paving the way for a better understanding of how wiring supports cognitive processes. While a large body of work now focuses on descriptive statistics to characterize these wiring patterns, a critical open question lies in how the organization of these networks constrains the potential repertoire of brain dynamics.  In this talk, I will describe an approach for understanding how perturbations to brain dynamics propagate through complex wiring patterns, driving the brain into new states of activity. Drawing on a range of disciplinary tools – from graph theory to network control theory and optimization – I will identify control points in brain networks and characterize trajectories of brain activity states following perturbation to those points. Finally, I will describe how these computational tools and approaches can be used to better understand the brain's intrinsic control mechanisms and their alterations in psychiatric conditions.

If you would like to attend the zoom meeting, send an email to and you will get the login details.